A 2025 University of Pennsylvania study found that higher exposure to fine particulate matter (PM2.5) in the year before death was associated with 19% higher odds of having more severe Alzheimer's-type brain changes.
January 01, 2025
high
temporal
Association derived from postmortem brain examinations linking recent PM2.5 exposure to Alzheimer's-type pathology.
A 2025 University of Pennsylvania study estimated that approximately 63% of the association between PM2.5 exposure and dementia severity was explained (mediated) by Alzheimer's-related brain pathology.
January 01, 2025
high
temporal
Quantifies the portion of the air pollution–dementia severity link attributable to Alzheimer's-type brain changes.
A 2025 University of Pennsylvania study examined postmortem brains from 602 people in the Penn Medicine Brain Bank and estimated individual PM2.5 exposure during the year before death using residential address.
January 01, 2025
high
temporal
Describes the study's sample size and the method used to estimate recent air pollution exposure.
A 2025 University of Pennsylvania study reported that among 287 individuals who had dementia assessments before death, higher PM2.5 exposure was associated with greater cognitive and functional decline, including memory loss, impaired judgment, and difficulty with personal care and speech.
January 01, 2025
high
temporal
Subgroup analysis linking higher recent PM2.5 exposure to worsened cognitive and daily-function outcomes in individuals with pre-death dementia assessments.
Approximately 40,000 dogs are used annually in research studies in the United States.
January 01, 2024
high
statistical
Commonly cited annual estimate of the number of dogs used in U.S. research studies
Beagles are a commonly used breed in veterinary and medical research and are used in studies of canine cancer.
January 01, 2024
high
descriptive
Breed-specific use in research, including oncology studies for dogs
A study analyzing the 2023 Florida reef heat wave (co-authored by the National Oceanic and Atmospheric Administration, the University of South Florida, and nonprofit organizations) estimated that between 97.8% and 100% of staghorn and elkhorn corals in the affected area died, leading researchers to characterize those species as functionally extinct in the Caribbean region.
January 01, 2023
high
statistical
Study of ecological impacts of the 2023 marine heat wave on Florida's reef.
A cohort study analyzing UK Biobank data that followed more than 120,000 adults over 10 years found that regular consumption of sugar-sweetened beverages was associated with about a 50% higher risk of metabolic dysfunction-associated steatotic liver disease (MASLD).
high
temporal
Longitudinal analysis of beverage consumption and liver outcomes using UK Biobank participants.
The cohort study analyzing UK Biobank data reported that replacing either sugar-sweetened beverages or low-/non-sugar-sweetened beverages with water was associated with up to a 15% reduction in risk of metabolic dysfunction-associated steatotic liver disease (MASLD), while substituting between sugar-sweetened and artificially sweetened beverages offered no risk reduction.
high
temporal
Comparative substitution analysis of beverage types and MASLD risk in the cohort study.
The Manhattan Project was a secret U.S. government program during World War II to develop atomic bombs.
high
contextual
Article references the Manhattan Project as a nearby historical site tied to atomic-bomb development.
Cesium-137 is a radioactive isotope produced by nuclear reactions.
high
scientific
General description of the origin of the isotope Cesium-137.
Cesium-137 is used in various industrial, medical, and research applications.
high
scientific
Common applications of the radioactive isotope Cesium-137.
A study published in the Proceedings of the National Academy of Sciences analyzed more than 12,000 MRI brain scans from nearly 5,000 healthy participants aged 17 to 95, with each participant having at least two scans taken over time.
high
temporal
Describes the study's sample size, age range, and longitudinal MRI data collection.
Coral bleaching occurs when corals expel their symbiotic algae, causing corals to appear white, reducing their nutrition and increasing their susceptibility to disease.
high
definitional
General biological process describing how warming waters affect coral health.