A 2024 study led by the University of Oxford in collaboration with Yale University and the University of Cambridge published in BMJ Evidence-Based Medicine analyzed data from more than 500,000 participants from the UK Biobank and the U.S. Million Veteran Program and from over 2.4 million participants across 45 studies to investigate links between genetically predicted alcohol consumption, alcohol use disorder, and dementia risk.
January 01, 2024
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Study design and sample sizes used to assess genetic and observational links between alcohol use and dementia
A cohort study analyzing UK Biobank data that followed more than 120,000 adults over 10 years found that regular consumption of sugar-sweetened beverages was associated with about a 50% higher risk of metabolic dysfunction-associated steatotic liver disease (MASLD).
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Longitudinal analysis of beverage consumption and liver outcomes using UK Biobank participants.
The cohort study analyzing UK Biobank data reported that replacing either sugar-sweetened beverages or low-/non-sugar-sweetened beverages with water was associated with up to a 15% reduction in risk of metabolic dysfunction-associated steatotic liver disease (MASLD), while substituting between sugar-sweetened and artificially sweetened beverages offered no risk reduction.
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Comparative substitution analysis of beverage types and MASLD risk in the cohort study.