Entity: Cleveland Clinic
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Cleveland Clinic

5 Facts
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Pertussis typically progresses through three stages: an initial phase with cold-like symptoms (runny nose, sneezing, mild cough), a second phase with severe coughing fits that may end in a high-pitched 'whoop', and a gradual recovery phase.
November 13, 2025 high clinical
Common clinical course of pertussis infections.
According to Johns Hopkins and the Cleveland Clinic, chronic venous insufficiency (CVI) occurs when veins in the legs do not function normally, leading to poor blood flow from the legs back to the heart.
October 09, 2025 high medical
Medical definition of chronic venous insufficiency cited by major medical centers.
The Cleveland Clinic describes a CKM syndrome staging system with stages 0–4: Stage 0 indicates no risk factors; Stage 1 indicates excess body fat; Stage 2 indicates presence of conditions such as type 2 diabetes, high blood pressure, or kidney disease; Stage 3 indicates subclinical heart disease or high risk of heart disease; and Stage 4 indicates symptomatic heart disease combined with excess body fat and metabolic risk factors, and may include kidney disease.
high classification
Clinical staging framework for assessing severity and presence of CKM-related risk factors and disease.
The Cleveland Clinic states that prostate cancer is the second-most common cancer affecting men, and that advancing age is the most common risk factor for prostate cancer.
high epidemiology
Prevalence and primary risk factor for prostate cancer.
Chronic venous insufficiency (CVI) occurs when veins in the legs are damaged, causing those veins to be unable to manage blood flow properly and potentially leading to swelling in the lower legs.
high medical_definition
Definition and common symptom of chronic venous insufficiency as described by a medical source.