Bone marrow can serve as a reservoir for dormant breast cancer cells, allowing tumor cells to persist in a quiescent state outside the primary tumor.
high
clinical
Clinical observation that disseminated breast cancer cells may be detectable in bone marrow.
Hormone therapy is the most effective treatment for menopausal hot flashes and night sweats, but it is generally unsuitable for women with a history of breast cancer because their cancer or its treatments typically lower or block estrogen.
high
treatment
Comparative suitability of hormone therapy for managing menopausal vasomotor symptoms
Clinical guidelines generally recommend prescribing hormone therapy for a limited duration to younger women in early or mid-stage menopause who do not have complicating risks such as a history of breast cancer or cardiovascular disease.
high
guideline
Standard-risk-based approach to menopausal hormone therapy in clinical practice.