Diabetes and Endocrinology

Stanford School of Medicine researchers report in the Journal of Clinical Investigation that a conditioning regimen to reset immunity, followed by bone marrow and donor islet-cell transplants, prevented or reversed Type 1 diabetes in mice. The team achieved 100% success in 19 pre‑diabetic mice and cured nine mice with established disease, with no major side effects reported, and say the approach could pave the way for human studies.