Study links 3–4 cups coffee to slower aging
Researchers at King’s College London report in BMJ Mental Health that among 436 adults with schizophrenia, bipolar disorder, or psychotic depression, drinking up to four cups of coffee daily was associated with longer telomeres—markers of cellular aging—equating to about five years younger biological age versus non‑drinkers. The observational study, published in late November 2025, found benefits peaked at three to four cups and reversed above four cups, aligning with FDA guidance of roughly 400 mg/day caffeine.
📌 Key Facts
- Population: 436 adults with severe mental illness (schizophrenia, bipolar disorder, psychotic depression).
- Association: 3–4 cups/day linked to longer telomeres (~5 years younger biological age vs. non‑drinkers).
- Threshold: Benefits disappeared above 4 cups/day, with signs of increased cellular stress.
- Publication: BMJ Mental Health, late November 2025; study is observational (cannot establish causation).
- Researchers cite coffee’s antioxidant/anti‑inflammatory compounds as potential mechanisms; quotes from Vid Mlakar and Dr. Monica Aas included.
📊 Relevant Data
Black Americans experience schizophrenia and related disorders at roughly twice the rate of White Americans.
America’s Hidden Racial Divide: A Mysterious Gap in Psychosis Rates — The New York Times
In 2022, White Americans constituted 59.2% of the US population, Black Americans 12.6%, Hispanic Americans 19.1%, Asian Americans 6.3%, and other groups the remainder.
Race and Ethnicity of the U.S. Population — American Council on Education
Major causes of reduced life expectancy in people with schizophrenia include cardiovascular disease, infections, respiratory diseases, cancer, and suicide.
Mortality in Schizophrenia-Spectrum Disorders: Recent Advances in Understanding and Management — Healthcare (Basel)