A 2025 study by researchers at the University of Osaka reported a protocol combining signaling molecules and other compounds that increases Foxp3 expression in induced regulatory T cells (iTregs), induces epigenetic modifications associated with Treg identity, and produced iTregs that maintained Foxp3 expression and provided immune-suppressive effects in mouse models for at least six weeks.
October 06, 2025
high
study
Core experimental findings on a method to stabilize iTregs reported in 2025