A 2025 10-week study led by researchers at McGill University of 92 healthy adults aged 65 or older found that doing rigorous cognitive training for 30 minutes per day increased acetylcholine levels by 2.3% in the anterior cingulate cortex.
October 22, 2025
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temporal
Acetylcholine was measured in the anterior cingulate cortex using PET imaging to assess the effect of targeted cognitive training.
Acetylcholine levels in some brain regions typically decline by approximately 2.5% per decade as part of normal aging.
October 22, 2025
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temporal
This rate is a commonly cited order-of-magnitude estimate for age-related decline in acetylcholine signaling in relevant brain areas.
A 2025 Pew Research Center survey found that 960,000 of the United States' Indian population of 4.9 million (approximately 20%) lived in California.
January 01, 2025
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statistical
Population distribution of Indian Americans by state according to a 2025 Pew survey.