The Johns Hopkins Bloomberg School of Public Health reports that mpox clade I is more likely to cause severe illness and death than clade II, with reported fatality rates for clade I ranging from 1% to 10% and for clade II ranging from less than 1% to 4%.
October 17, 2025
high
epidemiological
Comparative severity and reported fatality ranges for two genetic clades of the mpox virus as reported by a public health institution.