Entity: LDL cholesterol
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LDL cholesterol

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Heterozygous familial hypercholesterolemia (HeFH) is an inherited genetic condition that elevates low-density lipoprotein (LDL) cholesterol and increases the risk of early-onset heart disease.
high definition
Clinical definition and cardiovascular risk associated with HeFH
PCSK9-targeting lipid-lowering therapies and similar agents can produce reductions in low-density lipoprotein (LDL) cholesterol on the order of approximately 50–60% in treated patients.
high statistical
Typical magnitude of LDL cholesterol reduction achievable with PCSK9-targeting therapies