Obesity and Metabolic Health

Researchers from Washington University School of Medicine reported at the RSNA meeting in Chicago that Alzheimer’s blood biomarkers increased 95% faster over five years in people with obesity compared to non‑obese peers, based on 407 participants in the Alzheimer’s Disease Neuroimaging Initiative. PET scans in the same cohort showed greater amyloid plaque buildup in those with obesity, suggesting higher Alzheimer’s disease burden over time. The authors, Drs. Soheil Mohammadi and Cyrus Raji, said the results underscore the role of whole‑body health in brain health and called for future prevention trials, potentially including GLP‑1 drugs earlier in life.