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CDC Data Show 14 Percent Drop In U.S. Overdose Deaths In 2025

CDC preliminary data show U.S. street-drug overdose deaths fell about 14% in 2025 to 69,973, roughly 11,300 fewer deaths than in 2024.[1]

That 69,973 total is the lowest 12-month overdose death count in the U.S. since at least 2019.[1] The figure comes after a peak of 112,418 deaths in summer 2023.[1]

In recent reporting, experts linked the national decline to wider naloxone availability, expanded use of addiction medications, reports of less-potent illicit fentanyl, and reduced drug use among young people.[1]

The decline was uneven across states: Alabama, New York and Virginia recorded 25-30% drops in overdose deaths in the 12 months ending December 2025, while Arizona, New Mexico and North Dakota saw sharp increases.[1]

  1. NPR
Public Health Drug Policy and Addiction
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📌 Key Facts

  • CDC preliminary data report 69,973 U.S. street-drug overdose deaths in 2025, about 11,300 fewer than in 2024, a decline of roughly 14%.
  • The 2025 total is the lowest 12‑month overdose death count in the U.S. since at least 2019, down from a peak of 112,418 deaths in summer 2023.
  • Alabama, New York, and Virginia recorded 25–30% drops in overdose deaths in the 12 months ending December 2025, while Arizona, New Mexico, and North Dakota saw sharp increases.
  • Experts attribute the national decline to wider availability of naloxone, expanded use of addiction medications, less potent illicit fentanyl, and reduced drug use among young people.

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