South Carolina Measles Outbreak Hits 558 Cases as Vaccine Exemptions Rise
South Carolina health officials report 558 measles cases in a rapidly expanding outbreak centered in Spartanburg County, with 124 new infections in the past three days and 248 this week alone, making it the largest current measles outbreak in the U.S. At a Friday briefing, infectious‑disease specialist Dr. Helmut Albrecht warned the situation "is going to get worse before it gets better," noting hundreds of people statewide are already in quarantine or isolation and that at least six linked cases have appeared in neighboring North Carolina. State epidemiologist Linda Bell said most cases are in unvaccinated children and teens and that exposures have occurred in churches, restaurants, businesses and health‑care settings, while one local school’s vaccination rate is as low as 20%. Spartanburg County’s overall school vaccination rate is about 90%—below the 95% threshold needed for measles herd immunity—and nonmedical exemptions have jumped from roughly 3% of students in 2020 to about 8%, trends mirrored nationally in new JAMA research showing growing exemption clusters that leave counties vulnerable to outbreaks. The outbreak underscores how loosened or broadly granted nonmedical vaccine waivers are eroding protection against one of the most contagious human viruses, with local parents and teachers now publicly confronting school boards over what they call "absolute insanity" in exemption practices.
📌 Key Facts
- South Carolina has reported 558 measles cases as of Friday, with 124 new cases in the past three days and 248 this week.
- The outbreak’s epicenter is Spartanburg County, where overall student vaccination coverage is about 90%, below the 95% needed to block measles spread, and one school’s rate is around 20%.
- Nonmedical vaccine exemptions in Spartanburg County have risen to about 8% of students from roughly 3% in 2020, and at least six linked measles cases have already been detected in neighboring North Carolina.
📊 Relevant Data
Individuals with genetically defined African-American ancestry demonstrate significantly higher antibody (humoral) and cell-mediated (cellular) immune responses to measles vaccination compared to those with Caucasian ancestry.
Genetically defined race, but not sex, is associated with higher humoral and cellular immune responses to measles vaccination — ResearchGate
Nationally, childhood vaccination rates for the combined series vary by race and ethnicity, with Non-Hispanic White children at 75.5%, children of multiple races or other races at 73%, Asian children at 71%, Hispanic children at 68%, and Non-Hispanic Black children at 64%.
Childhood Vaccinations: Rates Vary By State, Ethnicity, Race — SHADAC
Spartanburg County's population has grown from 313,791 in 2020 to 338,096 in 2023, with a racial and ethnic composition of 67.7% White, 19.8% Black or African American, 8.8% Hispanic, and 2.5% Asian.
Spartanburg County, SC Population by Race & Ethnicity — Neilsberg
Nonmedical vaccine exemptions have increased in 53.5% of US counties by at least 1% when comparing 2010-2020 to 2021-2024, driven by post-COVID vaccine hesitancy.
Patches of low vaccination in the US are becoming bigger, riskier for outbreaks, study shows — CNN
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