November 22, 2025
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CDC flags new H3N2 variant; flu still low

The CDC said Friday that U.S. flu activity remains low but a new H3N2 subclade (K) is now driving most infections, with early analysis suggesting current vaccines offer partial protection. With holidays approaching, experts warn vaccination rates appear soft—especially in pharmacies—after last winter’s severe season, heightening risk for Twin Cities residents despite only one state (Louisiana) at moderate activity so far.

Health

📌 Key Facts

  • CDC surveillance (Nov. 21) shows a new H3N2 subclade K dominating recent cases; most infections so far are in children.
  • Early U.K. data suggest current flu shots provide at least partial protection against the new variant.
  • Last season saw unusually high hospitalizations and more than 18,000 flu-related deaths in the U.S.; Louisiana is currently the only state at moderate activity.
  • Pharmacy-administered flu shots are down by over 2 million versus last year through October (IQVIA), though CDC says child flu vaccination rates are roughly on par with last fall.

📰 Sources (1)